Bak DH, Yu KS, Jeong JH, Choi DR, Gil MN, Seo CM, Lee NS, Lee JH, Jeong YG, Kim DK, Kim DK, Kim JJ, Han SY. Autophagy enhancement contributes to synergistic effect of vitamin D in temozolomide-based glioblastoma chemotherapy. Exp Ther Med.
Jeong JH, Kim JJ*, Bak DH, Yu KS, Lee JH, Lee NS, Jeong YG, Kim DK, Kim DK, Han SY. Protective effects of indole-3-carbinol-loaded poly(lactic-co-glycolic acid) nanoparticles against glutamate-induced neurotoxicity. J Nanosci Nanotechnol.
Yang CS, Kim JJ, Kim TS, Lee PY, Kim SY, Lee HM, Shin DM, Nguyen LT, Lee MS, Jin HS, Kim KK, Lee CH, Kim MH, Park SG, Kim JM, Choi HS, Jo EK. Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome. Nat Commun. 2015 Feb 6;6:6115.
Blood-brain barrier-permeable fluorone-labeled dieckols acting as neuronal ER stress signaling inhibitors. JH Kwak, Z Yangb, B Yoon, Y He, S Uhm, H Shin, BH Lee, YC Yoo, KB Lee , JS Kim, SY Han, Biomaterials 61 (2015): 52–60
Synthesis of rhodamine-labelled dieckol: its unique intracellular localization and potent anti-inflammatory activity. JH Kwak, Y He, B Yoon, S Koo, Z Yang, EJ Kang, BH Lee, SYHan, YC Yoo, KB Lee, JS Kim, Chem commun 50 (2014): 13045-8
Neuroprotective Effect of Estradiol-Loaded Poly(lactic-co-glycolic acid) Nanoparticles on Glutamate-Induced Excitotoxic Neuronal Death. JH Kim, GH Kim, JH Jeong,IH Lee, YJ Lee, NS Lee, YG Jeong, JH Lee, KS Yu, SH Lee, SK Hong, SH Kang, BS Kang, DK Kim, SYHan, nanosci nanotech 14(2014): :8390-7
Yang CS, Kim JJ*, Lee HM, Jin HS, Lee SH, Park JH, Kim SJ, Kim JM, Han YM, Lee MS, Kweon GR, Shong MH, Jo EK. The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy. Autophagy. 2014 May; 10(5):785-802.
Protective Effects of Poly(lactic-co-glycolic acid) nanoparticles Loaded with Erythropoietin stabilized by Sodium Cholate Against glutamate-Induced Neurotoxicity. JH Jeong, SH Kang, JH Kim, KS Yu, IH Lee, YJ Lee, JH Lee, NS Lee, YG Jeong, DK Kim, GH Kim, SH Lee, SK Hong, BS Kang, SYHan, J nanosci nanotech 14(2014): 8365-71
So-An Park, Je-Hun Lee, Yeong-Seok Nam, Xiaochun An, Seung-Ho Han, Ki-Yong Ha. Topographical antomy of the anterior cervical approach for c2-3 level. European Spine Journal.
Je-Hun Lee, Be-Na Lee, Seung-Ho Han, Michael Y, Xiaochun An, pes anserine and anserine bursitis: anatomical study. Surgical and Radiologic Anatomy. In press
All-Trans-Retinoic Acid Rescues Neurons After Global Ischemia by Attenuating Neuroinflammatory Reactions. Neurochem Res DOI 10.1007/s11064-013-1178-x Springer Science+Business Media New York 2013
Je-Hun Lee, Be-Na Lee, Seung-Ho Han, Michael Y, Xiaochun An, The significance of tibial and common peroneal nerve in nerves block. Surgical and Radiologic Anatomy. 35:211-215 (2013)
Je-Hun Lee, Be-Na Lee, Seung-Ho Han. The effective zone of Botulinum toxin A injections in hallux claw toe syndrome: an anatomical study. Muscle and nerve. 45:217-221 (2012)
Research for Purkinje cell death of cerebellar ataxic mutant mice, Pogo, funded by Myung-gok medical research center (as a role of investigator in charge) ; 9/2010-8/2011
Sequence analysis of mutation in ataxic mice, Pogo originated from Korean wild mice and development of its behavioral test index, funded by Korea Ministry of education, sciece and technology (as a role of investigator in charge) ; 10/2010-5/2011
Study for neuroprotective effect and mechanism of various Ca2+ channel blockers: Using in vivo and ex vivo ischemic neuronal injury model, granted by Korea Research Foundation (as a role of investigator in charge)
Je-Hun Lee, Be-Na Lee, Seung-Ho Han, Xiaochun An, Rak-Hee Chung, The effective zone of Botulinum toxin A injections in the sternocleidomastoid muscle. Surgical and Radiologic Anatomy. 33:185-190 (2011)
Je-Hun Lee, Be-Na Lee, Xiaochun An, Rak-Hee Chung, Seung-Ho Han. Location of the motor entry point and intramuscular motor point of the tibialis posterior muscle: for effective motor point block. Clinical anatomy. 24:91-96(2011).
Je-Hun Lee, Be-Na Lee, Seoung-Oh Kwon, Rak-Hee Chung, Seung-Ho Han. Anatomical localization of submandibular gland for botulinum toxin injection. Surgical and Radiologic Anatomy. 32:945-949(2010)
Je-Hun Lee, Hye Won Kim, Sun Im, Xiaochun An, Mi-Sun Lee, Woo-Young Lee, Seung-Ho Han. Localization of Motor Points and Terminal Intramuscular Nerve Endings of the Musculocutaneous Nerve to Biceps and Brachialis Muscles. Surgical and Radiologic Anatomy 32. 213-220 (2010).
Xiaochun An, Je-Hun Lee, Hye Won Kim, Sun Im, Mi-Sun Lee, Kun Hwang, Seung-Ho Han. Anatomic Localization of Motor Entry Points and Intramuscular Nerve Endings in the Hamstring Muscles. Surgical and Radiologic Anatomy. 32.529-537. 2010.
Sun Im, Seung Ho Han, Jin Hwan Choi, Je Hun Lee, Young Jin Ko, Jong In Lee, Hye Won Kim. Anatomic Localization of Motor Points for the Neuromuscular Blockade of Hand Intrinsic Muscles Involved in Thumb-in-Palm. American J of Physl Med＆Rehabilitation.vol.87,No.9.September 2008
Yi-Suk Kim, Deog-Im Kim, Dae-Kyoon Park, Je-Hun Lee, Nak-Eun Chung, Won-Tae Lee, Seung-Ho Han. Assessment of Histomorphological Features of the Sternal End of the Fourth Rib for Age Estimation in Koreans. J Forensic Sci,November 2007,Vol.52,No.6
Je-Hun Lee, Deog-Im Kim, Yi-Suk Kim, Dae-Kyoon Park, Seung-Ho Han. The estimation of maximum femur length using long bone in Koreans. Korean J Phys Anthropol 18(4):247~254, 2005
A novel somatostatin-immunoreactive mossy fiber pathway associated with HSP25-immunoreactive purkinje cell stripes in the mouse cerebellum. J Comp Neurol. 2009; 1;517(4): 524-538
Striking pattern of Purkinje cell loss in cerebellum of an ataxic mutant mouse, tottering. Acta Neurobiol Exp. 2009; 69(1): 138-145.
Calbindin d-28k immunoreactivity and its protein level in hippocampal subregions during normal aging in gerbils. Cell Mol Neurobiol. 2009; 29(5): 665-672.
Indole-3-propionic acid attenuates neuronal damage and oxidative stress in the ischemic hippocampus. J Neurosci Res. 2009; 87(9): 2126-2137.
Pogo: a novel spontaneous ataxic mutant mouse. Cerebellum. 2009; 8(3): 155-162.
Tyrosine hydroxylase expression and Cdk5 kinase activity in ataxic cerebellum. Mol Cell Biochem. 2008; 318(1-2): 7-12.
Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya. Neuroscience. 2008; 27; 152(3): 609-617.
The neural mechanism of imagining facial affective expression. Brain Res. 2007; 1145: 128-137.
C-Fos expression in the periaqueductal gray is induced by electroacupuncture in the rat, with possible reference to GABAergic neurons. Okajimas Folia Anat Jpn. 2007; 84(1): 1-9.
The effect of prenatal X-irradiation on the developing cerebral cortex of rats. II: A quantitative assessment of glial cells in the somatosensory cortex. Int. J. Dev. Neurosci. 2007; 25(5): 293-297.
Increased serotonergic innervation of lumbosacral motoneurons of rolling mouse agoya in correlation with abnormal hindlimb extension. Anat. Histol. Embryol. 2006; 35(6): 387-392.The absence of phosphorylated tyrosine hydroxylase expression in the purkinje cells of the ataxic mutant pogo mouse. Anat. Histol. Embryol. 2006; 35(3): 178-183.
Corticotropin-releasing factor immunoreactivity increases in the cerebellar climbing fibers in the novel ataxic mutant mouse, pogo. Anat. Histol. Embryol. 2006; 35(2): 111-115.
Regional difference in corticotropin-releasing factor immunoreactivity in mossy fiber terminals innervating calretinin-immunoreactive unipolar brush cells in vestibulocerebellum of rolling mouse Nagoya. Brain Res. 2005; 1063: 96-101.
Tyrosine kinase A but not phosphacan/protein tyrosine phosphatase-zeta/beta immunoreactivity and protein level changes in neurons and astrocytes in the gerbil hippocampus proper after transient forebrain ischemia. Brain Res. 2005; 1036(1-2): 35-41.
Expression of epidermal growth factor in the developing rat kidney. Am. J. Physiol. Renal Physiol. 2005; 288(1): 227-235 .
Post-natal changes of cyclin-dependent kinase 5 activator expression in the developing rat cerebellum. Anat. Histol. Embryol. 2005; 34(1): 20-26.
Purkinje cell loss in the cerebellum of ataxic mutant mouse, dilute-lethal: a fractionator study. Congenit Anom (Kyoto). 2004; 44(4): 189-195.
Altered GABAB receptor immunoreactivity in the gerbil hippocampus induced by baclofen and phaclofen, not seizure activity. Neurosci Res. 2004; 49(4): 405-416.
Cdk5/p35 expression in the mouse ovary. Mol Cells. 2004; 17(1): 17-22.
Abnormal expression of tyrosine hydroxylase not accompanied by phosphorylation at serine 40 in cerebellar Purkinje cells of ataxic mutant mice, rolling mouse Nagoya and dilute-lethal. Congenit Anom (Kyoto). 2004; 44(1): 46-50.
Morphological characteristics of dopaminergic immunoreactive neurons in the olfactory bulb of the common marmoset monkey (Callithrix jacchus). Ann Anat. 2003 ; 185(6): 543-547.
Glutamate and GABA concentrations in the cerebellum of novel ataxic mutant Pogo mice. J Vet Sci. 2003; 4(3): 209-212.
Outer dense fibers serve as a functional target for Cdk5, p35 in the developing sperm tail. J Biol Chem. 2004; 279(2): 1224-1232.
The cyclin-dependent kinase 5 activator, p39, is expressed in stripes in the mouse cerebellum. Neuroscience 2003; 118(2): 323-334.
Bak DH, Zhang EJ, Yi MH, Kim DK, Han SY, Lim K, Kim JJ*, Kim DW. High w3-polyunsaturated fatty acids in fat-1 mice prevent streptozotocin-induced Purkinje cell degeneration through BDNF-mediated autophagy. Sci Rep. Oct 27;5:15465. doi: 10.1038/srep15465.
Kim MC, Liu MM, Sohn YJ, Kim JJ, Kang BS, Kim DK. Polyethyleneimine associated polycaprolactone (PCL)-superparamagnetic iron oxide nanoparticles (SPIONs) as a gene delivery vector. J Biomed Mater Res B Appl Biomater. Oct 6. doi: 10.1002/jbm.b.33519. [Epub ahead of print].
Park JN, Byun EB, Kim JJ, Jang BS, Park SH. Induction of apoptosis by gamma-irradiated apigenin of H1975 human non-small lung cell. J Korean Soc Food Sci Nutr. 2015: 44(6), 816-822.
특허
1. A Composition for enhancing anti-cancer effect of Temozolomide comprising 20(S)-protopanaxatriol and salt thereof. Patent Application No. 10-2015-0156097 (2015.11.06)
2. Composition comprising nanoparticle of Indole-3-carbinol for protecting neuronal cell. Patent Application No. 10-2015-0099982 (2015.07.14)
3. Composition comprising Indole-3-carbinol for protecting neuronal cell Patent Application No. 10-2015-0096748 (2015.07.07)
4. Combination comprising Temozolomide and Vitamin D for the treatment of glioblastoma Patent Application No. 10-2015-0090859 (2015.06.26)